Conditions Treated by Epilim Chrono CR

There are a number of causes for epilepsy, including an injury or damage to the brain, a structural abnormality, genetics, or a combination of any of these. Usually, the neurons in your brain produce electrochemical impulses that generate your thoughts, emotions, and actions. Epilepsy disturbs this normal pattern of neuronal activity and can result in the neurons firing more than twice as many times as it usually does and you have a seizure that causes your muscles to contract, visual disturbances, or you could blackout.

Injuries due to falls are possible during seizures. Many people take precautions by removing or padding the corners of sharp-edged furniture and blocking access to stairways to decrease the risk of injuries. Children may miss out of many activities for fear of an injury should they experience a seizure so some parents resort to having the child wear a bike helmet for protection.

Before Epilim Chrono CR is Prescribed

Your doctor may recommend taking a pregnancy test to confirm whether you are pregnant or not and advised to use a reliable birth control method during treatment with Epilim Chrono CR to avoid possible harm to an unborn baby. To determine if Epilim Chrono CR is right for you, tell your doctor about other medical conditions or allergies you have and mention any Rx drugs and non-prescription medications you take, including herbal remedies and dietary or vitamin supplements.

Epilim Chrono CR Precautions

Inform your doctor and dentist that you are taking Epilim Chrono CR if you are scheduled to undergo any surgical procedures with a general anesthetic so you can be instructed on when to take your medication. Do not stop taking Epilim Chrono CR or change your dosage without first talking to your doctor as this could initiate a seizure. All medications should be stored out of children’s reach and never share them with anyone else.

Possible Side Effects of Epilim Chrono CR

• Diarrhea
• Headache
• Drowsiness
• Irregular periods
• Nausea or vomiting
• Weight/appetite changes

Drugs Similar to Epilim Chrono CR

Each Tablet contains:
Sodium valproate……………..333/145mg

 COMPOSITION :
     Sodium valproate-200
Each film coated tablet contains
Sodium valproate I.P…….200 mg

     Sodium valproate-300
Each film coated tablet contains
Sodium valproate I.P……300 mg

     Sodium valproate-500
Each film coated tablet contains
Sodium valproate I.P……500 mg

     Sodium valproate CR-200
Each film coated tablet contains
Sodium valproate I.P……133.5 mg + Valproic acid
USP 58 mg (Both together correspond to Sodium Valproate 200 mg)

     Sodium valproate CR-300
Each film coated tablet contains
Sodium valproate I.P……200 mg + Valproic acid
USP 87 mg (Both together correspond to Sodium Valproate 300 mg)

     Sodium valproate CR-500
Each film coated tablet contains
Sodium valproate I.P……333 mg + Valproic acid
USP 145 mg (Both together correspond to Sodium Valproate 500 mg

  :
buy Sodium valproate valproate is the sodium salt of valproic acid and mechanisms by which valproate exerts its therapeutic effects have not been established. It has been suggested that its activity in epilepsy is related to increased brain concentrations of gamma-aminobutyric acid (GABA).

       For more information, please see Full Prescribing Information.

 INDICATIONS :
Epilepsy
Sodium valproate is indicated as monotherapy and adjunctive therapy in the treatment of patients with complex partial seizures that occur either in isolation or in association with other types of seizures.

Sodium valproate is also indicated for use as sole and adjunctive therapy in the treatment of simple and complex absence seizures, and adjunctively in patients with multiple seizure types that include absence seizures

Mania
Sodium valproate is indicated for the treatment of the manic episodes associated with bipolar disorder.

Migraine
Sodium valproate  is indicated for prophylaxis of migraine headaches.

The recommended initial dose is 15 mg/kg/day buy Sodium valproate  increasing at one week intervals by 5 to 10 mg/kg/day until seizures are controlled or side effects preclude further increases. The maximum recommended dosage is 60 mg/kg/day. If the total daily dose exceeds 250 mg, it should be given in divided doses. DOSAGE AND ADMINISTRATION :
Sodium valproate tablets are administered orally.

buy Sodium valproate  Antiepileptic drugs should not be abruptly discontinued in patients in whom the drug is administered to prevent major seizures because of the strong possibility of precipitating status epilepticus and attendant hypoxia and threat to life. In epileptic patients previously receiving Sodium valproate therapy, Sodium valproate tablets should be initiated at the same daily dose and dosing schedule. After the patient is stabilized on Sodium valproate tablets, a dosing schedule of two or three times a day may be elected in selected patients

 CONTRAINDICATIONS :
Sodium valproate should not be administered to patients with hepatic disease or significant hepatic dysfunction. Sodium valproate is contraindicated in patients with known hypersensitivity to the drug

 PRECAUTIONS :
Hepatic failure resulting in fatalaties has occurred in patients receiving sodium valproate. These incidents usually have occurred during the first six months of treatment. Serious or fatal hepatotoxicity may be preceded by non-specific symptoms such as malaise, weakness, lethargy, facial oedema, anorexia and vomiting. In patients with epilepsy, a loss of seizure control may also occur.

The benefits of the therapy should be weighed against the risks. Above this age group, experience in epilepsy has indicated that the incidence of fatal hepatotoxicity decreases considerably in progressively older patient groups. The drug should be discontinued immediately, in the presence of significant hepatic dysfunction suspected or apparent. In some cases, hepatic dysfunction has progressed in spite of discontinuation of drug.

 SIDE EFFECT :
The common adverse events reported during sodium valproate therapy include nausea, somnolence, dizziness, vomiting, asthenia, abdominal pain, dyspepsia, rash and mania.

 PACKAGING INFORMATION :
Sodium valproate-200 Blister strip of 10’s
Sodium valproate-300 Blister strip of 10’s
Sodium valproate-500 Blister strip of 10’s

Sodium valproate CR-200 Blister strip of 10’s
Sodium valproate CR-300 Blister strip of 10’s
Sodium valproate CR-500 Blister strip of 10’s